Transgender PrEP Study

Get PrEP at no cost for participation in a research study!

Enrollment for our study is currently OPEN. However, due to COVID-19 changes there may be delays or temporary pauses in enrollment.

We are looking for transgender and gender non-binary individuals to join our study for PrEP switch study.

Our study will require that participants take/have taken Truvada® for at least 12 weeks* then switch to Descovy®. Descovy® is a medication that had been recently approved by the FDA for PrEP. However, while Descovy® has been approved for PrEP with most types of sex, Descovy® has not yet been approved for PrEP with insertive vaginal sex. More information can be found on the “About Descovy®” page. If you are interested in the study but unsure if Descovy® is right for you, please leave your contact information below or contact us. Study staff will review details with you to see if the study is right for you.

*If you have been taking Truvada® continuously for at least 3 months, you may be able to switch directly to Descovy® at your first visit. If you have taken Truvada® for less than 3 months, you may be able to join the study while you continue to take Truvada® from your provider, and then switch to Descovy® after 3 months. Study staff will be able to let you know if this is possible.

If you are interested in joining the study but not yet on Truvada®, feel free to contact us and we can get you connected to a PrEP provider.

What does the study involve?

  • Six or seven IN-PERSON visits over a one-year period
  • Take Truvada® for 12 weeks then switch to Descovy® for 48 weeks
  • Descovy®, HIV/STI testing, and safety labs at no cost
  • Daily text reminders to take PrEP for at least 12 weeks
  • Answer surveys about your sexual health

Eligibility Requirements

  • Age 18 or older
  • Identify as transgender or nonbinary
  • HIV- negative
  • Currently taking or able to start on Truvada®
  • Willing to switch to Descovy®

Interested in participating?

If you live in San Diego, please contact:

Jordan at (619) 543-3198 or